Johnny Silva Cancer Research

myocarditis

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Several studies (in both humans and a murine model) have established that cTnI and cTnT are superior to CK-MB for detection of myocyte injury in myocarditis (Fig. 6) (3841). Cardiac troponin monitoring provided sensitive evidence of clinically suspected myocarditis in the first month after the onset of heart failure symptoms. However, as for other

methods for the diagnosis of myocarditis, negative results do not exclude the presence of the disease. Nevertheless, the finding of increased levels of troponin in patients with a clinical story consistent with myocarditis is associated with a higher probability of histological or immunohistological evidence of myocarditis on endomyocardial biopsy. A correlation of troponin concentration and the severity of myocarditis has not been consistently observed.